系统性评估DNA语言模型预训练对下游微调任务的影响，揭示不同预训练策略的效果差异。
arXiv:2606.30140v1 Announce Type: cross Abstract: Recent breakthroughs in foundation models and Large Language Models (LLMs) have introduced new oppor…
RNA设计新算法登场，用“蒙帕纳斯”策略优化序列二级结构，计算生物学前沿突破。
arXiv:2606.07562v1 Announce Type: cross Abstract: RNA design consists of discovering a nucleotide sequence that optimizes predefined criteria, such as…
CryoProt创新地利用冷冻电镜密度图与跨盒交互机制，为蛋白质预训练提供了新思路，值得AI生物研究者关注。
arXiv:2606.00955v1 Announce Type: new Abstract: Despite the growing availability of cryo-electron microscopy (cryo-EM) density maps, effectively lever…
前沿论文揭示：大语言模型智能体能自动完成自然语言表型到本体的标注，告别人工瓶颈！
arXiv:2605.28965v1 Announce Type: new Abstract: Linking free-text phenotype descriptions to ontology terms, typically referred to as phenotype annotat…
小语言模型学会分子语法，高效生成药物分子候选，AI+化学新突破。
arXiv:2605.06322v2 Announce Type: replace Abstract: Language models for molecular design have scaled to hundreds of millions of parameters, yet how th…
基于大语言模型的多智能体框架，实现质谱代谢组学知识图谱的高效交互分析，开辟生物数据解读新路径。
arXiv:2510.01724v2 Announce Type: replace Abstract: Mass spectrometry-based metabolomics generates complex, high-dimensional data that holds vast pote…
用文本信息检索酶反应，提出通用化框架TIGER，被ACL 2026接收，生物与NLP交叉新范式。
arXiv:2605.24489v1 Announce Type: new Abstract: Enzyme-reaction retrieval is a fundamental problem in computational biology, underpinning enzyme chara…
构建大规模非冗余蛋白质折叠分类基准TEDBench，突破尺度瓶颈，助力生物大分子功能解析。
arXiv:2605.18552v1 Announce Type: new Abstract: Classifying protein topology is essential for deciphering biological function, but progress is held ba…
花几百美元测了全基因组，拿到VCF文件后，如何挖掘其中99%的隐藏信息？
Published May 20, 2026 on matbanik.info You paid somewhere between $300 and $500 for whole genome sequencing. Maybe Nebula, maybe Dante, maybe one of …
AI驱动DNA研究助手开源发布，结合大模型优化生物信息分析工作流。
Article URL: https://codeberg.org/rlipas/dnagent Comments URL: https://news.ycombinator.com/item?id=48206613 Points: 2 # Comments: 0
首个蛋白质构象集合的tokenizer，突破静态结构局限，捕捉动态运动与替代状态。
arXiv:2605.13789v2 Announce Type: replace-cross Abstract: Protein structure tokenizers (PSTs) are workhorses in protein language modeling, function pr…